However, with many studies and over sixty years of experience with the use of natural progesterone, it is clear that the low level of progesterone is the main cause of these ailments. This is due to the lack of ovulation cycles during which the progesterone was produced from the corpus luteum.

The absence of cycles results in a drastic decrease in production and consequently, progesterone deficiency and its antagonistic effects on oestrogen hormones that are still produced by the ovaries. In addition, the lack of adequate amounts of progesterone causes abnormalities throughout the woman’s entire hormonal system.

This is because progesterone is a precursor of other steroid hormones such as estradiol, estriol, estron, testosterone, cortisol, corticosterone, aldosterone, DHEA. In addition, due to a decrease in the production of sex hormones, mainly progesterone and oestrogens, the secretion of other hormones such as FSH (follicle stimulating hormone) and LH (luteinizing hormone), which stimulate the ovaries to produce sex hormones, is clearly increasing in the pituitary gland.

On the one hand, lower level of sex hormones, on the other hand, more stimulatory hormones secreted by the pituitary gland – produce a number of unpleasant and serious ailments. Supplementation during this period with natural progesterone (premenopause, perimenopause, menopause, postmenopausal period) allows very effective inhibition of pituitary hormone secretion FSH and LH.

Progesterone allows the production of adequate and balanced amounts of the remaining steroid hormones in the body. Their production is strictly regulated, and in the case of precursor deficiency, that is, progesterone, their production is disturbed and causes a number of very serious ailments.

Natural progesterone administered during this period acts on the remaining hormones. Progesterone protects against harmful side effects, caused by excess cortisol, pituitary hormones and adrenal cortical hormones and can also compensate for their deficiency.

The onset of hormonal imbalance in women can occur after 35 years of age. It follows that the symptoms of menopause may appear for 10-20 years before the menopause. The cause of hormonal imbalance is the so-called anovulatory cycles. Despite regular menstruation, there may be no ovulation; ovarian release from the ovary. Ovulation is a necessary condition for the formation of so called ovary’s yellow corpus, the place where progesterone is produced.

In the absence of ovulation, the yellow body is not formed and progesterone is not produced. The level in the body is very low. There is a situation in which high levels of oestrogen are not balanced by the right amount of progesterone. This gives rise to the syndrome of oestrogen dominance and the onset of symptoms typical of climacteric.

Anovulation periods may be regular or irregular and may show differences in menstrual bleeding, making it heavier and longer. Although the first anovulation cycles may occur as early as 30 years of age, the menopause happens at about 50 years old. After the appearance of anovulation cycles, the osteoporosis process begins. The cause of this process is of course the lack of progesterone – bone building hormone.

Many women enter the age of the proper climacteric with bone loss of up to 25-30%. The initial stages of breast, uterine or cervical cancer usually occur five or more years before menopause, which is long before the oestrogen level drops but coincides with the decrease in progesterone levels.

Osteoporosis and natural progesterone.

Osteoporosis results from systematic loss of bone mass in relation to age, sex and race. Bone mass is less saturated, lighter, more porous, so the bone is often broken, even without injury. Loss of bone density begins many years before menopause (even a dozen or so years). How does bone tissue undergo osteoporosis? Bones are living tissue and are constantly undergoing resorption and reconstruction. Responsible for this are two types of cells: osteoclasts and osteoblasts.

The first ones look for places to rebuild and reshape the old tissue, leaving empty spaces behind. Then the osteoblasts appear, building a new bone. These processes take place throughout life, but in different periods one of them may overweigh. The period of bone growth has the advantage of forming new bone tissue. After puberty it comes to a balance. From around 35 years of age, the balance shifts to decay, which is initially slow, and the closer to menopause, the faster it shifts.

People with osteoporosis are unaware of the risk, as the disease progresses asymptomatically until the bone is broken. Advanced stage osteoporosis can result in fracture of the femoral neck under only the weight of the body. It is one of the most common diseases that women suffer. The main cause of osteoporosis is a high protein diet. Meat (including fish and poultry), eggs, milk and dairy products are the most important causes of bone loss.

In societies that live on a vegetarian, non-dairy diet, osteoporosis occurs very rarely. Smoking, alcohol, coffee and carbonated drinks also cause more than average calcium loss. Lack of physical exercise also contributes to a greater than usual loss of bone tissue.

The leader in natural progesterone therapy, Dr. John R. Lee was in the mid 70s facing a serious dilemma. Patients with osteoporosis came to him. They were mostly women during menopause. He could have prescribed oestrogen, exposing them to the risk of endometrial cancer or breast cancer and many other diseases.

Then, after studying the professional literature, numerous clinical studies and listening to many lectures, he started using a second hormone, which levels down during the climacteric period – progesterone (natural, in cream). The results exceeded all his expectations. Some patients achieved 105% of the average bone calcification for females of 35 years of age.

All women, who used natural progesterone, experienced bone growth of 5 to 40% between 6 months and 4 years. Fractures due to osteoporosis have dropped to zero. When administered oestrogen, the bone density remained unchanged or very slightly decreased. Oestrogen only inhibited the process and progesterone reversed it. At the same time, patients described many unrelated but positive effects of the treatment: cyst degeneration, reduction of multiple serious “gynaecological symptoms”, as well as reduction of hair loss, acne or water retention.